Description
Book Synopsis: Cluster Randomised Trials discusses the design, conduct, and analysis of health trials that randomise groups of individuals to different treatments. It explores the advantages of cluster randomization, with special attention given to evaluating the effects of interventions against infectious diseases. Avoiding unnecessary mathematical detail, the book covers basic concepts underlying the use of cluster randomisation, such as direct, indirect, and total effects. The authors also present an array of design issues in cluster randomised trials (CRTs), including strategies for minimizing contamination effects, the use of stratification and restricted randomisation to improve balance between treatment arms, special methods for sample size calculation, and alternatives to the simplest two-arm CRT.
After covering analytical methods for CRTs, such as regression methods, the authors examine ethical issues, trial monitoring, interim analyses, reporting, and interpretation. Although the book mainly focuses on medical and public health applications, it shows that the rigorous evidence of intervention effects provided by CRTs has the potential to inform public policy in a wide range of other areas. The book encourages readers to apply the methods to their own trials, reproduce the analyses presented, and explore alternative approaches.
Details
Discover the power of cluster randomization with Cluster Randomised Trials (Chapman & Hall/CRC Biostatistics Series). This comprehensive book delves into the design, conduct, and analysis of health trials that randomize groups of individuals to different treatments. With a special focus on evaluating the effects of interventions against infectious diseases, this book is an indispensable resource for anyone in the medical and public health field.
Cluster Randomised Trials breaks down complex concepts into easily understandable language, making it accessible to researchers and practitioners alike. We've intentionally avoided unnecessary mathematical detail, ensuring that you can grasp the key concepts and put them into practice right away.
One of the major advantages of cluster randomization is the ability to assess direct, indirect, and total effects. You'll learn how to harness the power of this approach to obtain rigorous evidence of intervention effects, which can inform public policy in various areas beyond just medical and public health. The potential impact of your research is limitless!
Throughout this book, you'll also find valuable insights on design issues, such as minimizing contamination effects, improving balance between treatment arms through stratification and restricted randomization, and calculating sample sizes effectively. We leave no stone unturned, equipping you with a comprehensive toolkit for successful cluster randomised trials.
The authors of Cluster Randomised Trials also cover the analytical methods necessary for conducting and analyzing CRTs. From regression methods to ethical considerations, trial monitoring to interim analyses, this book provides you with all the tools you need to ensure the validity and reliability of your research.
Ready to take your research to the next level? Apply the methods outlined in Cluster Randomised Trials to your own trials, reproduce the analyses presented, and explore alternative approaches. Join countless researchers who have already benefited from this knowledge and make a lasting impact.
Get your copy of Cluster Randomised Trials today and unlock the potential of cluster randomization in your research projects!
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