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Research - Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity (Advances in Experimental Medicine and Biology, 1043)

Description

Book Synopsis: The book provides a reference for years to come, written by world-renowned expert investigators studying sex differences, the role of sex hormones, the systems biology of sex, and the genetic contribution of sex chromosomes to metabolic homeostasis and diseases. In this volume, leaders of the pharmaceutical industry present their views on sex-specific drug discovery. Many of the authors presented at the Keystone Symposium on “Sex and gender factors affecting metabolic homeostasis, diabetes and obesity” to be held in March 2017 in Lake Tahoe, CA. This book will generate new knowledge and ideas on the importance of gender biology and medicine from a molecular standpoint to the population level and to provide the methods to study them. It is intended to be a catalyst leading to gender-specific treatments of metabolic diseases. There are fundamental aspects of metabolic homeostasis that are regulated differently in males and females, and influence both the development of diabetes and obesity and the response to pharmacological intervention. Still, most preclinical researchers avoid studying female rodents due to the added complexity of research plans. The consequence is a generation of data that risks being relevant to only half of the population. This is a timely moment to publish a book on sex differences in diseases as NIH leadership has asked scientists to consider sex as a biological variable in preclinical research, to ensure that women get the same benefit of medical research as men.

Details

Discover the groundbreaking insights into metabolic homeostasis, diabetes, and obesity with our latest release Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity. This insightful book, authored by world-renowned expert investigators in sex differences, offers a comprehensive reference for years to come. Uncovering the role of sex hormones, genetic contributions, and the systems biology of sex, this volume is a game-changer in understanding gender-specific treatments of metabolic diseases.

What sets our book apart is the collaboration of leaders from the pharmaceutical industry, delivering their perspectives on sex-specific drug discovery. Drawing from the highly-anticipated Keystone Symposium on "Sex and gender factors affecting metabolic homeostasis, diabetes, and obesity," this book captures the cutting-edge research that will shape the future of gender biology and medicine from the molecular level to the whole population.

One significant aspect explored in this book is the regulatory differences in metabolic homeostasis between males and females. By shedding light on these fundamental variances, we unlock the door to better understand the development of diabetes and obesity and improve the efficacy of pharmacological interventions. We acknowledge that historically, researchers have avoided studying female rodents due to the complexities it brings to research plans. However, this has led to a generation of data that only represents half of the population.

Now, as the NIH calls upon scientists to consider sex as a vital biological variable in preclinical research, it's a timely opportunity to delve into the intricacies of sex differences in diseases. By understanding sex-specific factors, we can ensure that women receive the same benefits from medical research as men. Be a part of this transformative movement and join us in exploring the revolutionizing discoveries presented in Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity.

Don't miss out on this groundbreaking publication! Order your copy now and be at the forefront of gender-specific treatments, shaping the future of medicine!

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