Best Sellers in Books
Discover the most popular and best selling products in Books based on sales

Disclosure: I get commissions for purchases made through links in this website
Research - Precision Medicine in Neurodegenerative Disorders: Part II (Volume 193) (Handbook of Clinical Neurology, Volume 193)

Description

Book Synopsis: Precision Medicine in Neurodegenerative Disorders, Part Two, Volume 193 in the Handbook of Clinical Neurology deals with the "How" in the reconfiguration of our approach to slow accelerated brain aging. The book rethinks animal models on which therapies are tested, outlines the progress and expected changes in biological subtyping efforts using lysosomal, endosomal, mitochondrial, immune dysregulation, and inflammatory mechanisms of disease pathophysiology, and the growing role of microbiome in shaping disease. The volume separates the potentially disease-modifying neurorescue and neurorestoration, (e.g., gene therapy and cell replacement therapy) from true precision "medicine"–matching biology with the mechanism of intervention of interest. Specific chapters are dedicated to the promise and challenges of extracellular vesicles for both diagnosis and treatment, the growing application of digital measures and other evaluations of clinical response, the nuts and bolts of novel adaptive clinical trial designs, and the regulatory changes needed to facilitate drug development for disease-modification purposes. Summarizes theory and research on precision medicine in neurodegenerative disorders. Covers basic biology, clinical trials and therapeutics. Includes disease mechanisms, genetic subtypes, and more. Read more.

Details

Precision Medicine in Neurodegenerative Disorders, Part II (Volume 193) is a groundbreaking book that delves into the "How" of slowing down accelerated brain aging. In this Handbook of Clinical Neurology volume, our expert authors challenge traditional approaches to therapies by rethinking animal models. They outline the progress and expected changes in biological subtyping efforts, with a focus on disease pathophysiology such as lysosomal, endosomal, mitochondrial, immune dysregulation, and inflammatory mechanisms. Furthermore, this volume explores the significant role of the microbiome in shaping these disorders.

This book goes beyond the conventional disease-modifying approaches. It explores the potential of neurorescue and neurorestoration, including gene therapy and cell replacement therapy. By matching biology with the intervention mechanism, the true precision "medicine" is achieved. Our expert authors dedicate specific chapters to the promise and challenges of extracellular vesicles for diagnosis and treatment. Additionally, the book explores the growing applications of digital measures and other evaluations of clinical response.

The Handbook of Clinical Neurology, Volume 193, also discusses novel adaptive clinical trial designs. It provides valuable insights into regulatory changes required for efficient drug development for disease-modification purposes. Stay at the forefront of the field with this comprehensive and compelling guide to precision medicine in neurodegenerative disorders.

Don't miss the opportunity to gain a deeper understanding of precision medicine and its implications for neurodegenerative disorders. Take the first step towards enhancing patient care and transforming the field by reading Precision Medicine in Neurodegenerative Disorders: Part II (Volume 193) now.

Buy now

Disclosure: I get commissions for purchases made through links in this website